Endocrine Man

Endocrine control of skeletal development in man.

to produce intracellular oedema: this should be minimal when a twin-coil ultrafiltration artificial kidney (Aoyama and Kolff, 1957) is used, because this machine can effectively remove water at a rate of 800 ml./hour. Anima! experiments (Alexander et al., 1961) have shown that intravenous infusions of urea, similar to those used to decrease brain bulk at craniotomy (Stubbs and Penny-backer, 196...

Endocrine Man: A Study in the Surgery of Sex

Corticosteroids in Endocrine Diseases

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The silent spermatozoon: are man-made endocrine disruptors killing male fertility?

I n 1992, a Danish group led by Skakkebaek reported in a meta-analysis that global mean spermcountswerefallingandthattesticularcancer, hypospadias and cryptorchidism were increasing. They hypothesized that environmental factors were the cause. Their metaanalysis was criticized subsequently for many methodological flaws. However, their controversial meta-analysis and hypothesis spurred public an...

Fleshy papules in areas of friction in a man with endocrine neoplasms.

Histologic evaluation of biopsy specimens from both the neck and the abdomen demonstrated an expansile dermis composed of thick whorls of collagen bundles consistent with collagenomas (Figure 3). The presence of cutaneous collagenomas and multiple endocrine neoplasms is most consistent with MEN1. Subsequent genetic analysis of MEN1 was positive for a heterozygous deletion (c.1670-1672delAGA) kn...